Dissolution DNP can be used in combination with ex vivo organ perfusions to measure central carbon metabolism in real time. Applying Dynamic Nuclear Polarization to Measure Pancreatic Metabolism using Hyperpolarized PyruvateĪnna Rushin, Dalton Graham, Matthew Merrittĭynamic Nuclear Polarization (DNP) transfers polarization from a free radical electron to a coupled nuclear spin bath, significantly enhancing the signal in the resulting nuclear magnetic resonance (NMR) spectra.